Recent study shows Mini-Gastric Bypass is a "simpler and safer procedure that has no disadvantage compared with laparoscopic Roux-en-Y gastric bypass."

The study was a prospective, randomized trial to compare treatments of morbid obesity.

The group compared the safety and effectiveness of laparoscopic Roux-en-Y gastric bypass and Mini-Gastric Bypass in the treatment of morbid obesity.
Laparoscopic Roux-en-Y gastric bypass has been the gold standard for the treatment of morbid obesity.

The Mini-Gastric Bypass has been reported to be a simple and effective treatment, the team report that data from a randomized trial are lacking.

The study randomized 80 patients, 40 patients to receive laparoscopic Roux-en-Y gastric bypass and 40 to Mini-Gastric Bypass.

The minimum postoperative follow-up was two years.

The researchers determined late complication, excess weight loss, body mass index, quality of life, and comorbidities. Changes in quality of life were assessed using the Gastro-Intestinal Quality of Life Index.

The only conversion was in the laparoscopic Roux-en-Y gastric bypass group.

The operation time was shorter in Mini-Gastric Bypass group and there was no mortality in either group.

The operative morbidity rate was higher in the laparoscopic Roux-en-Y gastric bypass group, at 20 percent versus only 8 percent in the MGB group.

The late complications rate was the same in the two groups at 8 percent with no re-operation.

The weight loss was 59 percent and 60 percent at one and two years, respectively, in the laparoscopic Roux-en-Y gastric bypass group.

The percentage weight loss in the group was 65 percent and 64 percent in the Mini-Gastric Bypass group.

Residual excess weight of less than 50 percent at two years postoperatively was achieved in 75 percent of patients in the laparoscopic Roux-en-Y gastric bypass group.

In comparison, the residual excess weight loss at two years in the Mini-Gastric Bypass group was 95 percent.

A significant improvement of obesity-related clinical parameters and complete resolution of metabolic syndrome in both groups were noted. In addition, the researchers observed that gastrointestinal quality of life increased significantly without any significant difference between the groups.

Annals of Surgery; 2005: 242(1): 20-8

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